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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEPCE
All Species:
16.67
Human Site:
S353
Identified Species:
40.74
UniProt:
Q7L2J0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L2J0
NP_062552.2
689
74355
S353
P
P
A
A
S
V
I
S
A
P
P
S
S
S
S
Chimpanzee
Pan troglodytes
XP_527836
689
74350
S353
P
P
A
A
S
V
I
S
A
P
P
S
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001104039
689
74134
S353
P
P
A
A
S
V
T
S
A
P
P
S
S
S
S
Dog
Lupus familis
XP_546957
692
75135
S351
P
P
A
A
S
V
T
S
A
T
P
S
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3A9
666
72032
S330
P
P
A
A
S
V
T
S
A
P
S
T
S
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505557
496
54391
R194
T
R
G
P
A
P
P
R
S
R
P
D
R
N
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921729
629
69161
L316
P
T
P
P
T
K
R
L
I
T
H
T
Q
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K480
1367
146215
L564
T
P
A
E
E
M
L
L
S
C
S
A
T
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U2R0
378
44095
N74
K
S
E
K
P
A
E
N
S
P
F
K
K
N
Q
Sea Urchin
Strong. purpuratus
XP_789930
553
61051
P251
K
I
V
S
P
V
L
P
D
S
R
G
R
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.4
91.6
N.A.
87
N.A.
N.A.
30.9
N.A.
N.A.
43.5
N.A.
21.8
N.A.
26.4
30.6
Protein Similarity:
100
99.4
98.5
93.5
N.A.
89.6
N.A.
N.A.
37.1
N.A.
N.A.
56.8
N.A.
31.6
N.A.
37.4
45.7
P-Site Identity:
100
100
93.3
86.6
N.A.
80
N.A.
N.A.
6.6
N.A.
N.A.
6.6
N.A.
20
N.A.
6.6
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
N.A.
N.A.
26.6
N.A.
N.A.
26.6
N.A.
60
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
60
50
10
10
0
0
50
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% D
% Glu:
0
0
10
10
10
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
20
0
10
0
0
0
0
0
0
% I
% Lys:
20
0
0
10
0
10
0
0
0
0
0
10
10
10
0
% K
% Leu:
0
0
0
0
0
0
20
20
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
20
0
% N
% Pro:
60
60
10
20
20
10
10
10
0
50
50
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% Q
% Arg:
0
10
0
0
0
0
10
10
0
10
10
0
20
0
10
% R
% Ser:
0
10
0
10
50
0
0
50
30
10
20
40
50
60
50
% S
% Thr:
20
10
0
0
10
0
30
0
0
20
0
20
10
10
0
% T
% Val:
0
0
10
0
0
60
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _